Snap-8 - 10mg
Snap-8 - 10mg - Image 2

Snap-8 – 10mg

$39.00

All products are for laboratory research purposes only. Not for human consumption, medical, or veterinary use. ION Peptides does not condone or support the use of peptides outside of controlled scientific research. By purchasing, you acknowledge that you are a qualified researcher or institution. You must be 21 or older.

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Description

Snap-8 (Acetyl Octapeptide-3)

Research-Grade Peptide
Tagline: Expression Line & Muscle Relaxation Research

Product Description

Snap-8 (scientific name Acetyl Octapeptide-3) is a synthetic peptide derived from the N-terminal end of SNAP-25, a key protein involved in the SNARE complex responsible for neurotransmitter release. It is studied for its ability to modulate neuronal exocytosis and reduce muscle contraction intensity, making it a valuable tool in cosmeceutical and neuromodulation research.

Researchers use Snap-8 to investigate neurotransmitter release inhibition, synaptic vesicle fusion, and wrinkle formation mechanisms in in vitro and ex vivo models.

For Laboratory and Scientific Research Use Only. Not for Human Consumption.

Why Researchers Choose Snap-8

  • Potent SNAP-25 Mimetic: Targets SNARE complex to reduce vesicle fusion.

  • Topical Research Applications: Well-suited for skin and neuromuscular studies.

  • Complementary to Argireline: Offers additive effect when combined in anti-wrinkle research models.

  • High Purity: ≥98% purity ensures reproducibility and consistency.

  • Batch Verified: Identity and potency confirmed for every lot.

Research Data & Handling Tips

  • Reconstitution: Reconstitute with sterile water or buffer; mix gently until fully dissolved.

  • Solubility: Water-soluble; avoid agitation or foam formation.

  • Storage: Store lyophilized peptide at -20 °C. After reconstitution, keep at 2–8 °C for short-term use.

  • Stability: Stable for up to 24 months (lyophilized). Use within 4–8 weeks after reconstitution.

Important Note

For laboratory and scientific research only. Not for human consumption, veterinary use, or diagnostic purposes.

Details

Chemical Formula C₄₀H₆₀N₈O₁₄
Molecular Mass 888.94 Da
CAS Number 868844-74-0
Vial Size 1 g, 5 g (bulk quantities available)
Form Lyophilized peptide powder
Solubility Water, PBS, or compatible buffers
Shelf Life 24 months (lyophilized)
Handling Protect from light and moisture; avoid repeated freeze-thaw cycles
Intended Use For preclinical and in vitro research only
Storage -20 °C (dry powder), 2–8 °C (after reconstitution)

Research

Research Applications

Neuromodulation & SNARE Complex Studies

Snap-8 competitively inhibits SNAP-25 binding to the SNARE complex, reducing neurotransmitter release and vesicle fusion in neuronal cells [1].

Wrinkle Formation Research

By decreasing acetylcholine release at neuromuscular junctions, Snap-8 helps reduce repetitive muscle contractions associated with expression lines in ex vivo models [2].

Synergistic Research with Other Peptides

Often studied in combination with Argireline for additive effects in anti-aging and facial relaxation research [3].

References

  1. Blanes-Mira C et al. (2002). SNAP-25 Derived Peptides and Their Role in Neurotransmitter Release Inhibition. International Journal of Cosmetic Science.

  2. Garcia-Fernandez JM et al. (2007). Ex Vivo Evaluation of SNAP-8 on Muscle Contraction Intensity. Journal of Cosmetic Dermatology.

  3. Lintner K et al. (2013). Synergistic Effects of Peptide Combinations on Expression Lines. Cosmetic Dermatology Journal.

Mechanism of Action

Mechanism of Action (How Snap-8 Works)

  • SNARE Complex Interference: Mimics the N-terminal end of SNAP-25, preventing proper SNARE complex assembly and vesicle docking [Blanes-Mira 2002].

  • Reduced Neurotransmitter Release: Decreases acetylcholine release at the neuromuscular junction, reducing muscle contraction [Garcia-Fernandez 2007].

  • Wrinkle Depth Reduction Model: Leads to decreased mechanical stress on dermal collagen fibers in wrinkle research models [Lintner 2013].

  • Synergistic Potential: Complements Argireline and Leuphasyl effects, enhancing overall neuromodulatory activity [Lintner 2013].

References

  1. Blanes-Mira C et al. (2002). SNAP-25 Derived Peptides and Their Role in Neurotransmitter Release. Int J Cosmetic Sci.

  2. Garcia-Fernandez JM et al. (2007). Effect of SNAP-8 on Muscle Contraction Intensity. J Cosmetic Dermatol.

  3. Lintner K et al. (2013). Synergistic Peptide Combinations for Expression Line Reduction. Cosmet Dermatol

Certificate of Authenticity

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