Selank Spray 10mg

Selank Spray 10mg

$59.95

All products are for laboratory research purposes only. Not for human consumption, medical, or veterinary use. ION Peptides does not condone or support the use of peptides outside of controlled scientific research. By purchasing, you acknowledge that you are a qualified researcher or institution. You must be 21 or older.

Our Spray Kits Come unassembled. They include
– Selank 10mg Vial
– 3ML Luer Lock Syringe
– Spray Bottle
– 10ML Bacteriostatic Water

Only 10 left in stock

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Description

Selank Spray (10 mg)

Research-Grade Heptapeptide Nasal Formula
Tagline: Anxiolytic & Cognitive Research

Product Description

Selank is a synthetic analog of the immunomodulatory peptide tuftsin, developed in Russia to explore neuropsychiatric, cognitive, and immune modulation pathways. In nasal spray format, it provides a non-invasive delivery route for central nervous system access.

Researchers use Selank nasal spray to investigate its effects on anxiety modulation, memory enhancement, neuroprotection, and immunoregulatory signaling in in vivo and ex vivo models.

For Laboratory and Scientific Research Use Only. Not for Human Consumption.

Why Researchers Choose Selank Nasal Spray

  • Rapid CNS Access: Intranasal delivery may bypass first-pass metabolism and support central effects.

  • Anxiolytic Profile: Reports suggest anti-anxiety action without sedation.

  • Cognitive Benefits: Studied for improving memory, learning, and mood stability.

  • Immunomodulation: Potential to influence cytokine balance and immune response.

  • High Purity: Manufactured to research-grade standards with peptide verification.

Research Data & Handling Tips

  • Formulation: 10 mg peptide pre-dissolved for nasal administration.

  • Solubility: Compatible with aqueous saline buffers.

  • Storage: Refrigerate (2–8 °C), protect from light.

  • Stability: Use within shelf-life (manufacturer dependent).

  • Handling: Ensure sterility, do not freeze.

Important Note

For laboratory and scientific research only. Not for human consumption, therapeutic, or diagnostic use.

Details

Formulation Type Pre-formulated nasal spray solution
Peptide Content 10 mg Selank per vial
Chemical Formula C₃₃H₅₇N₁₁O₉
Molecular Mass ~751.9 Da
Appearance Clear, colorless aqueous solution
Intended Research Use Anxiety, cognition, neuroprotection, immune modulation
Storage Conditions Refrigerated (2–8 °C), protected from light
Handling Do not freeze; handle aseptically
Vial Size 10 mL

Research

Research Applications

Anxiety & Mood Regulation
Selank has been studied for its anxiolytic effects: in human and animal trials, it showed reduced anxiety without sedation, possibly via modulation of GABAergic and serotonin systems. [Filatova et al. 2017]

Cognitive Enhancement & Memory
Selank has been shown to increase expression of BDNF in hippocampal regions and improve memory retention in stress-induced cognitive decline models. [Inozemtseva et al. 2008]

Immune & Inflammatory Modulation
Derived from tuftsin, Selank exhibits immunoregulatory activity—modulating cytokine levels (e.g., IL-6) in stress models and influencing T-cell responses. [Volkova et al. 2016]

Neuroprotection & Stress Resilience
In preclinical studies, Selank showed protective effects in neuronal injury and chronic stress models, reducing cell death, stabilizing neurotransmitters, and preserving neuronal architecture. [Markov et al. 2023]

References

  1. Filatova E, et al. (2017). GABA, Selank, and Olanzapine Affect the Expression of Genes Involved in GABAergic Neurotransmission in IMR-32 Cells. Frontiers in Pharmacology.
    https://www.frontiersin.org/articles/10.3389/fphar.2017.00089/full

  2. Inozemtseva LS, et al. (2008). Intranasal administration of the peptide Selank regulates BDNF expression in the rat hippocampus in vivo. Doklady Biological Sciences.
    https://pubmed.ncbi.nlm.nih.gov/18806861

  3. Volkova A, et al. (2016). Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission. Frontiers in Pharmacology.
    https://www.frontiersin.org/articles/10.3389/fphar.2016.00031/full

  4. Markov DD, et al. (2023). The Melanocortin System: A Promising Target for the Development of New Antidepressant Drugs. International Journal of Molecular Sciences.
    https://www.mdpi.com/1422-0067/24/7/6664

Mechanism of Action

Mechanism of Action (How Selank Works)

  • GABAergic Modulation: Influences GABA-A receptor activity and GABA neurotransmission to produce anxiolytic effects. [Filatova et al. 2017]

  • Serotonin & Dopamine Regulation: Modulates levels of serotonin and dopamine in various brain regions, contributing to mood stability. [Wholistic Research, summary of mechanistic hypotheses]

  • BDNF Upregulation: Enhances expression of brain-derived neurotrophic factor, supporting synaptic plasticity and memory processes. [Inozemtseva et al. 2008]

  • Immunoregulatory Actions: Mimics tuftsin’s immune signaling, modulating cytokine production and T-cell balance, particularly in stress or inflammatory states. [Volkova et al. 2016]

  • Neuroprotective Signaling: Stabilizes neuronal environment under stress, reducing oxidative damage, and supporting cell survival pathways. [Markov et al. 2023]

References

  1. Filatova E, et al. (2017). GABA, Selank, and Olanzapine Affect the Expression of Genes Involved in GABAergic Neurotransmission in IMR-32 Cells. Frontiers in Pharmacology.
    https://www.frontiersin.org/articles/10.3389/fphar.2017.00089/full

  2. Inozemtseva LS, et al. (2008). Intranasal administration of the peptide Selank regulates BDNF expression in the rat hippocampus in vivo. Doklady Biological Sciences.
    https://pubmed.ncbi.nlm.nih.gov/18806861

  3. Volkova A, et al. (2016). Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission. Frontiers in Pharmacology.
    https://www.frontiersin.org/articles/10.3389/fphar.2016.00031/full

  4. Markov DD, et al. (2023). The Melanocortin System: A Promising Target for the Development of New Antidepressant Drugs. International Journal of Molecular Sciences.
    https://www.mdpi.com/1422-0067/24/7/6664

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