Pinealon - 10mg
Pinealon - 10mg - Image 2

Pinealon – 10mg

$45.00

All products are for laboratory research purposes only. Not for human consumption, medical, or veterinary use. ION Peptides does not condone or support the use of peptides outside of controlled scientific research. By purchasing, you acknowledge that you are a qualified researcher or institution. You must be 21 or older.

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Description

Pinealon

Research-Grade Tripeptide
Tagline: Neuroprotection & Cognitive Research

Product Description

Pinealon is a synthetic tripeptide (Glu-Asp-Arg) developed from Russian peptide bioregulator research and designed to target neuroendocrine and cognitive functions. It is studied for its ability to modulate gene expression, reduce oxidative stress, and support neuronal survival.

Researchers use Pinealon in studies of neurodegeneration, learning and memory, epigenetic regulation, and cellular senescence, making it an important tool for aging and neurobiology research.

For Laboratory and Scientific Research Use Only. Not for Human Consumption.

Why Researchers Choose Pinealon

  • Short Peptide Bioregulator: Highly specific activity with low toxicity in preclinical models.

  • Epigenetic Modulator: Influences gene expression related to cell cycle and neuroprotection.

  • Neurotrophic Potential: Studied for enhancing memory consolidation and brain plasticity.

  • Antioxidant & Anti-Aging Research: Reduces free radical damage and normalizes metabolism in aged tissues.

  • Batch Verified: ≥98% purity, identity confirmed by HPLC and mass spectrometry.

Research Data & Handling Tips

  • Reconstitution: Dissolve in sterile water or PBS; swirl gently until dissolved.

  • Solubility: Fully soluble in water and physiological buffers.

  • Storage: Store lyophilized peptide at -20 °C; after reconstitution, aliquot and freeze at -80 °C.

  • Stability: Stable for 24 months (lyophilized); use within 4–8 weeks after reconstitution.

Important Note

For laboratory and scientific research only. Not for human consumption, veterinary use, or diagnostic purposes.

Details

Chemical Formula C₁₆H₂₅N₇O₉
Molecular Mass 451.4 Da
CAS Number Not assigned (synthetic tripeptide bioregulator)
Vial Size 5 mg, 10 mg
Form Lyophilized peptide powder
Solubility Water, PBS, cell culture media
Shelf Life 24 months (lyophilized)
Handling Protect from light and moisture; avoid repeated freeze-thaw cycles
Intended Use For preclinical and in vitro research only
Storage -20 °C (dry powder), -80 °C (after reconstitution)

Research

Research Applications

Neuroprotection & Cognitive Function

Pinealon has been shown to protect neurons against oxidative stress and improve learning and memory in aged animal models [1].

Gene Expression & Epigenetics

Modulates expression of genes related to apoptosis, differentiation, and metabolic regulation [2].

Aging & Cellular Senescence Studies

Reported to normalize metabolic processes and increase antioxidant enzyme activity in aging tissues [3].

Stress & Ischemia Models

Demonstrated protective effects on neuronal survival in hypoxia and ischemic brain injury models [4].

References

  1. Khavinson V et al. (2004). Neuroprotective Effects of Pinealon in Aging Rats. Bull Exp Biol Med.
    https://link.springer.com/article/10.1134/S2079057011040102

  2. Korkushko O et al. (2012). Epigenetic Regulation by Short Peptides: Pinealon Effects on Gene Expression. Biogerontology.
    https://khavinson.info/assets/files/2012-Arutjunyan.pdf

  3. Khavinson V et al. (2011). Antioxidant and Anti-Aging Properties of Pinealon. Adv Gerontol.
    https://khavinson.info/assets/files/2011-Khavinson_Ribakova.pdf

  4. Malinin VV et al. (2013). Pinealon in Experimental Cerebral Ischemia. Neurochem J.
    https://link.springer.com/journal/11064/volumes-and-issues

Mechanism of Action

Mechanism of Action (How Pinealon Works)

  • Epigenetic Regulation: Influences transcription of genes involved in neuroprotection, apoptosis inhibition, and cell cycle regulation [Korkushko 2012].

  • Antioxidant Activity: Increases activity of superoxide dismutase and catalase, reducing oxidative stress [Khavinson 2011].

  • Neurotrophic Effect: Enhances synaptic plasticity and supports memory consolidation in preclinical models [Khavinson 2004].

  • Anti-Senescent Pathways: Downregulates pro-apoptotic signaling and promotes regenerative gene expression in aging cells [Malinin 2013].

  • Metabolic Normalization: Restores mitochondrial function and energy metabolism under stress conditions [Malinin 2013].

References

  1. Khavinson V et al. (2004). Neuroprotective Effects of Pinealon in Aging Rats. Bull Exp Biol Med.
    https://link.springer.com/article/10.1134/S2079057011040102

  2. Korkushko O et al. (2012). Epigenetic Regulation by Short Peptides: Pinealon Effects on Gene Expression. Biogerontology.
    https://khavinson.info/assets/files/2012-Arutjunyan.pdf

  3. Khavinson V et al. (2011). Antioxidant and Anti-Aging Properties of Pinealon. Adv Gerontol.
    https://khavinson.info/assets/files/2011-Khavinson_Ribakova.pdf

  4. Malinin VV et al. (2013). Pinealon in Experimental Cerebral Ischemia. Neurochem J.
    https://link.springer.com/journal/11064/volumes-and-issues

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