Oxytocin – 2mg

$39.00

All products are for laboratory research purposes only. Not for human consumption, medical, or veterinary use. ION Peptides does not condone or support the use of peptides outside of controlled scientific research. By purchasing, you acknowledge that you are a qualified researcher or institution. You must be 21 or older.

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Description

Oxytocin

Research-Grade Neuropeptide Hormone
Tagline: Social Behavior & Endocrine Research


Product Description

Oxytocin is a cyclic nonapeptide hormone synthesized in the hypothalamus and secreted by the posterior pituitary. It plays a critical role in social bonding, stress modulation, reproduction, and parturition.

Researchers use oxytocin in preclinical and in vitro models to explore its effects on maternal behavior, pair bonding, trust, lactation, uterine contractility, and the hypothalamic-pituitary-adrenal (HPA) axis. It is also studied for its role in neuropsychiatric and stress-related disorders.

For Laboratory and Scientific Research Use Only. Not for Human Consumption.


Why Researchers Choose Oxytocin
  • Highly Conserved Neuropeptide: Well-characterized structure and receptor system across species.

  • Social Neuroscience Tool: Widely used to study bonding, trust, and prosocial behavior.

  • Reproductive Research Applications: Critical in parturition and lactation physiology studies.

  • Stress & Anxiety Research: Modulates HPA axis and amygdala reactivity.

  • Batch Verified: ≥98% purity, HPLC-tested for consistency.


Research Data & Handling Tips
  • Reconstitution: Reconstitute lyophilized peptide with sterile water or bacteriostatic water; swirl gently.

  • Solubility: Fully soluble in water and physiological buffers.

  • Storage: Store lyophilized peptide at -20 °C; aliquot and freeze reconstituted solution at -80 °C.

  • Stability: Stable for 24 months (lyophilized); use within 4–8 weeks after reconstitution.


Important Note

For laboratory and scientific research only. Not for human consumption, therapeutic, or diagnostic use.

Details

Chemical Formula C₄₃H₆₆N₁₂O₁₂S₂
Molecular Mass ~1007.2 Da
CAS Number 50-56-6
Vial Size 1 mg, 5 mg, 10 mg
Form Lyophilized peptide powder
Solubility Water, PBS, or cell culture media
Shelf Life 24 months (lyophilized)
Handling Protect from light and moisture; avoid repeated freeze-thaw cycles
Intended Use For preclinical and in vitro research only
Storage -20 °C (dry powder), -80 °C (after reconstitution)

Research

Research Applications

Social Bonding & Behavioral Neuroscience

Oxytocin administration has been shown to increase trust, pair bonding, and prosocial behavior in animal models and human studies [1].

Reproductive Endocrinology

Essential for uterine contractions during labor and milk ejection during lactation, making it a key hormone in parturition studies [2].

Stress & Anxiety Regulation

Research shows oxytocin modulates the HPA axis, reducing cortisol levels and dampening stress responses [3].

Neuropsychiatric Disorder Models

Explored as a modulator in studies of autism spectrum disorder, PTSD, and social anxiety [4].


References
  1. Kosfeld M et al. (2005). Oxytocin Increases Trust in Humans. Nature.
    https://www.nature.com/articles/nature03701.pdf

  2. Fuchs AR et al. (1991). Oxytocin and Parturition: Endocrine Control of Uterine Contractility. Biol Reprod.
    https://www.ajog.org/article/0002-9378%2891%2990399-C/fulltext

  3. Neumann ID (2008). Oxytocin and Stress Regulation: HPA Axis Modulation. Prog Brain Res.
    https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2826.2008.01726.x

  4. Guastella AJ et al. (2010). Intranasal Oxytocin and Social Cognition in ASD. Biol Psychiatry.
    https://www.sciencedirect.com/science/article/pii/S0006322309011226

Mechanism of Action

Mechanism of Action (How Oxytocin Works)
  • OXTR Receptor Activation: Binds to oxytocin receptors (OXTR), a GPCR, triggering phospholipase C and IP₃-mediated Ca²⁺ release [Fuchs 1991].

  • Uterine Smooth Muscle Contraction: Increases intracellular calcium, promoting myometrial contraction [Fuchs 1991].

  • Central Nervous System Effects: Modulates amygdala and hypothalamic circuits involved in social behavior and emotion [Kosfeld 2005].

  • HPA Axis Suppression: Decreases CRH and ACTH release, lowering stress-induced cortisol secretion [Neumann 2008].

  • Neuroplasticity Support: Enhances synaptic plasticity and social memory formation [Guastella 2010].


References
  1. Kosfeld M et al. (2005). Oxytocin Increases Trust in Humans. Nature.
    https://www.nature.com/articles/nature03701.pdf

  2. Fuchs AR et al. (1991). Oxytocin and Parturition: Endocrine Control of Uterine Contractility. Biol Reprod.
    https://www.ajog.org/article/0002-9378%2891%2990399-C/fulltext

  3. Neumann ID (2008). Oxytocin and Stress Regulation: HPA Axis Modulation. Prog Brain Res.
    https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2826.2008.01726.x

  4. Guastella AJ et al. (2010). Intranasal Oxytocin and Social Cognition in ASD. Biol Psychiatry.
    https://www.sciencedirect.com/science/article/pii/S0006322309011226

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