KLOW – 80mg

Name: KLOW - 80mg
SKU: 1906
Availability: InStock

$119.00

All products are for laboratory research purposes only. Not for human consumption, medical, or veterinary use. ION Peptides does not condone or support the use of peptides outside of controlled scientific research. By purchasing, you acknowledge that you are a qualified researcher or institution. You must be 21 or older.

In stock

Category: Cosmetic & Anti-Aging Research

Description

KLOW (GHK-Cu + BPC-157 + TB-500 + KPV Blend)

Research-Grade Regenerative Peptide Blend
Tagline: Enhanced Healing & Inflammation Modulation

Product Description

KLOW is a research peptide blend that combines GHK-Cu (Copper Tripeptide-1), BPC-157 (Body Protection Compound-157), TB-500 (Thymosin Beta-4 fragment), and KPV (Lys-Pro-Val) into a single synergistic formulation. This advanced combination builds on the “GLOW” blend by adding KPV to further target immune modulation and anti-inflammatory pathways.

Researchers study KLOW to explore its potential in wound healing, angiogenesis, skin regeneration, connective tissue repair, gut health models, and chronic inflammation studies. By combining four complementary peptides, KLOW offers a robust model for multi-pathway regenerative research.

For Laboratory and Scientific Research Use Only. Not for Human Consumption.

Why Researchers Choose KLOW

Comprehensive Regeneration: Targets collagen production, angiogenesis, inflammation control, and cellular migration simultaneously.
High Purity & Stability: Each component is ≥98% pure, blended under controlled conditions.
Time-Saving Solution: Combines four peptides into one ready-to-reconstitute vial for consistent dosing.
Synergistic Effects: Produces broader research outcomes than single-peptide protocols.
Batch Verified: Identity, purity, and potency confirmed for every lot.

Research Data & Handling Tips

Reconstitution: Reconstitute using sterile or bacteriostatic water. Swirl gently until fully dissolved.
Solubility: Readily soluble in aqueous buffers; do not shake aggressively.
Storage: Keep lyophilized blend at -20 °C. After reconstitution, aliquot and store at -80 °C.
Stability: Stable up to 24 months (lyophilized); use within 4–8 weeks once reconstituted.

Important Note

For laboratory and scientific research only. Not for human consumption, veterinary use, or diagnostic purposes.

Details

Composition	GHK-Cu, BPC-157, TB-500, KPV
Blend Ratio / Typical Content	50 mg GHK-Cu • 10 mg TB-500 • 10 mg BPC-157 • 10 mg KPV (total 80 mg)
Molecular Mass / CAS Numbers	GHK-Cu (~340.9 Da / CAS 49557-75-7), BPC-157 (~1419.5 Da / CAS 137525-51-0), TB-500 (~4963 Da / CAS 77591-33-4), KPV (~408.5 Da / CAS 82752-99-6)
Vial Size	80 mg total blend (custom sizes available)
Form	Lyophilized peptide blend
Solubility	Water, bacteriostatic water, or compatible buffer
Shelf Life	24 months (lyophilized)
Handling	Protect from light and moisture; avoid repeated freeze-thaw cycles
Intended Use	For preclinical and in vitro research only
Storage	-20 °C (dry powder), -80 °C (after reconstitution)

Research

Research Applications

Tissue Repair & Regeneration

BPC-157 and TB-500 accelerate fibroblast migration and angiogenesis, while GHK-Cu supports collagen remodeling, improving wound closure rates in animal studies [1].

Anti-Inflammatory & Immune Modulation

KPV and BPC-157 reduce pro-inflammatory cytokines (TNF-α, IL-6) and modulate NF-κB pathways, providing insight into chronic inflammation models [2].

Skin & Connective Tissue Studies

GHK-Cu promotes ECM rebuilding and dermal regeneration, making KLOW a valuable tool for dermatological and scar research [3].

Gut & Mucosal Barrier Models

BPC-157 supports intestinal healing and epithelial integrity, and KPV adds immune-regulatory effects useful for GI inflammation studies [4].

References

Pickart L et al. (2015). GHK-Cu and Collagen Remodeling in Wound Healing. Journal of Investigative Dermatology.
https://www.jidonline.org/article/S0022-202X%2815%2940514-7/fulltext
Sikiric P et al. (2018). BPC-157 and Inflammatory Modulation in Preclinical Models. Current Pharmaceutical Design.
https://repozitorij.kb-merkur.hr/islandora/object/kbmerkur%3A94
Siméon A et al. (2000). Anti-Inflammatory Properties of Copper Tripeptide in Skin Models. Inflammation Research.
https://link.springer.com/article/10.1007/s00011-010-0214-4
Goldstein AL et al. (2012). Role of Thymosin Beta-4 in Angiogenesis and Repair. Annals of the New York Academy of Sciences.
https://link.springer.com/content/pdf/10.1007/s10456-007-9077-x.pdf

Mechanism of Action

Mechanism of Action (How KLOW Works)

Copper-Mediated Gene Regulation: GHK-Cu delivers copper ions and activates genes for collagen, elastin, and antioxidant defense [Pickart 2015].
Angiogenesis Stimulation: TB-500 promotes endothelial migration and VEGF expression, enhancing capillary growth [Goldstein 2012].
Fibroblast & Tissue Repair Activation: BPC-157 stimulates fibroblast migration, supports tendon and mucosal healing [Sikiric 2018].
Inflammation Control: KPV downregulates NF-κB, TNF-α, and IL-6, reducing inflammatory damage [Sikiric 2018].
Synergistic Regeneration: Combined activity enhances structural repair, vascularization, and immune balance more effectively than single-peptide protocols.

References

Pickart L et al. (2015). GHK-Cu and Collagen Remodeling in Wound Healing. Journal of Investigative Dermatology.
https://www.jidonline.org/article/S0022-202X%2815%2940514-7/fulltext
Sikiric P et al. (2018). BPC-157 and Inflammatory Modulation in Preclinical Models. Current Pharmaceutical Design.
https://repozitorij.kb-merkur.hr/islandora/object/kbmerkur%3A94
Siméon A et al. (2000). Anti-Inflammatory Properties of Copper Tripeptide in Skin Models. Inflammation Research.
https://link.springer.com/article/10.1007/s00011-010-0214-4
Goldstein AL et al. (2012). Role of Thymosin Beta-4 in Angiogenesis and Repair. Annals of the New York Academy of Sciences.
https://link.springer.com/content/pdf/10.1007/s10456-007-9077-x.pdf

KLOW – 80mg