GHRP-6 - 5mg
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GHRP-6 – 5mg

$19.00

All products are for laboratory research purposes only. Not for human consumption, medical, or veterinary use. ION Peptides does not condone or support the use of peptides outside of controlled scientific research. By purchasing, you acknowledge that you are a qualified researcher or institution. You must be 21 or older.

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Description

GHRP-6 (Growth Hormone Releasing Peptide-6)

Research-Grade Hexapeptide
Tagline: GH Secretion & Appetite Research

Product Description

GHRP-6 (Growth Hormone Releasing Peptide-6) is a synthetic hexapeptide and potent ghrelin receptor (GHS-R1a) agonist, widely used in research to study growth hormone (GH) secretion, appetite regulation, and metabolic signaling.

Researchers utilize GHRP-6 in preclinical and in vitro models to explore GH axis physiology, IGF-1 production, ghrelin-mediated hunger response, and tissue regeneration pathways. Its activity makes it a valuable tool in endocrinology, metabolism, and muscle growth studies.

For Laboratory and Scientific Research Use Only. Not for Human Consumption.

Why Researchers Choose GHRP-6

  • Potent GH Secretagogue: Stimulates pulsatile GH release via pituitary and hypothalamic pathways.

  • Ghrelin Receptor Agonist: Activates GHS-R1a, enabling appetite and metabolic research.

  • Synergistic Potential: Often studied with GHRH analogues like Sermorelin or CJC-1295 for amplified GH release.

  • Muscle & Tissue Research: Used to model GH/IGF-1–driven recovery and regeneration.

  • Batch Verified: ≥98% purity, tested by HPLC and mass spectrometry.

Research Data & Handling Tips

  • Reconstitution: Reconstitute with bacteriostatic water; swirl gently until dissolved.

  • Solubility: Fully soluble in water or PBS.

  • Storage: Store lyophilized peptide at -20 °C; aliquot and store reconstituted solution at -80 °C.

  • Stability: Stable for 24 months (lyophilized); use within 4–8 weeks once reconstituted.

Important Note

For laboratory and scientific research only. Not for human consumption, veterinary use, or diagnostic purposes.

Details

Chemical Formula C₄₆H₅₆N₁₂O₆
Molecular Mass 873.0 Da
CAS Number 87616-84-0
Vial Size 5 mg, 10 mg
Form Lyophilized peptide powder
Solubility Water, PBS, or compatible buffer
Shelf Life 24 months (lyophilized)
Handling Protect from light and moisture; avoid repeated freeze-thaw cycles
Intended Use For preclinical and in vitro research only
Storage -20 °C (dry powder), -80 °C (after reconstitution)

Research

Research Applications

Growth Hormone Axis Studies

GHRP-6 stimulates GH release independently of GHRH, providing a model to study pituitary responsiveness and GH pulsatility [1].

IGF-1 Production & Anabolism

Used in studies to measure downstream effects on hepatic IGF-1 production and protein synthesis [2].

Appetite & Ghrelin Research

Activates ghrelin receptors, increasing hunger and food intake in animal models — useful in cachexia and metabolism research [3].

Muscle & Tissue Regeneration

Explored for its ability to accelerate muscle repair and connective tissue recovery through GH/IGF-1 pathways [4].

References

  1. Smith RG et al. (1997). GHRP-6 as a Potent GH Secretagogue. Endocrinology.
    https://link.springer.com/chapter/10.1007/978-1-59259-015-5_2

  2. Bowers CY et al. (1990). GHRP-6 and IGF-1 Production in Humans. J Clin Endocrinol Metab.
    https://karger.com/hrp/article/51/Suppl.%203/1/371582/Growth-Hormone-Releasing-Substances-Types-and

  3. Kojima M et al. (1999). Discovery of Ghrelin and its Receptor. Nature.
    https://reference.medscape.com/medline/abstract/10604470

  4. Nass R et al. (2008). GH Secretagogues and Tissue Repair Models. Hormone Research.
    https://link.springer.com/chapter/10.1007/978-1-59259-015-5_3

Mechanism of Action

Mechanism of Action (How GHRP-6 Works)

  • Ghrelin Receptor Agonism: Binds GHS-R1a on pituitary somatotrophs and hypothalamic neurons, triggering GH release [Smith 1997].

  • Synergistic with GHRH: Acts via a distinct receptor pathway, amplifying GH pulse amplitude when combined with GHRH analogues [Bowers 1990].

  • Hypothalamic Stimulation: Reduces somatostatin tone, increasing net GH secretion [Smith 1997].

  • Hunger Signaling: Activates hypothalamic NPY/AgRP neurons, stimulating appetite [Kojima 1999].

  • Anabolic Pathways: Leads to elevated IGF-1 and enhanced protein synthesis, supporting muscle and tissue repair [Nass 2008].

References

  1. Smith RG et al. (1997). GHRP-6 as a Potent GH Secretagogue. Endocrinology.
    https://link.springer.com/chapter/10.1007/978-1-59259-015-5_2

  2. Bowers CY et al. (1990). GHRP-6 and IGF-1 Production in Humans. J Clin Endocrinol Metab.
    https://karger.com/hrp/article/51/Suppl.%203/1/371582/Growth-Hormone-Releasing-Substances-Types-and

  3. Kojima M et al. (1999). Discovery of Ghrelin and its Receptor. Nature.
    https://reference.medscape.com/medline/abstract/10604470

  4. Nass R et al. (2008). GH Secretagogues and Tissue Repair Models. Hormone Research.
    https://link.springer.com/chapter/10.1007/978-1-59259-015-5_3

Certificate of Authenticity

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