GHK-Cu - 50mg
GHK-Cu - 50mg - Image 2

GHK-Cu – 50mg

$24.00

All products are for laboratory research purposes only. Not for human consumption, medical, or veterinary use. ION Peptides does not condone or support the use of peptides outside of controlled scientific research. By purchasing, you acknowledge that you are a qualified researcher or institution. You must be 21 or older.

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Description

GHK-Cu (Copper Tripeptide-1)

Research-Grade Copper Peptide
Tagline: Regenerative Research Peptide

Product Description

GHK-Cu (Copper Tripeptide-1) is a naturally occurring copper-binding peptide consisting of the amino acid sequence glycyl-L-histidyl-L-lysine complexed with copper (II). It is widely studied for its potential role in tissue remodeling, wound healing, and anti-inflammatory processes.

Researchers use GHK-Cu in preclinical studies to investigate its effects on collagen synthesis, angiogenesis, and cellular regeneration. Its unique ability to modulate gene expression and bind copper ions makes it a valuable tool for studies in dermatology, regenerative medicine, and anti-aging research.

For Laboratory and Scientific Research Use Only. Not for Human Consumption.

Why Researchers Choose GHK-Cu

  • High Purity: ≥98% purity ensures reproducible results.

  • Biologically Relevant: Mimics a naturally occurring peptide-copper complex.

  • Stability: Supplied in lyophilized form for maximum shelf life.

  • Easy Handling: Simple reconstitution and compatibility with aqueous buffers.

  • Research Versatility: Studied in wound healing, tissue regeneration, and hair follicle biology.

  • Batch Tested: Each lot undergoes rigorous identity and purity verification.

Research Data & Handling Tips

  • Reconstitution: Dissolve in sterile water or PBS. Mix gently until fully dissolved.

  • Solubility: Soluble in aqueous solutions. Avoid repeated freeze-thaw cycles.

  • Storage: Store lyophilized powder at -20 °C. After reconstitution, aliquot and store at -80 °C.

  • Stability: Stable for up to 24 months (lyophilized). Use reconstituted solution within 4–8 weeks.

Important Note

For laboratory and scientific research only. Not for human consumption, veterinary use, or diagnostic purposes.

Details

Chemical Formula C₁₄H₂₄CuN₆O₄
Molecular Mass 340.9 g/mol
CAS Number 49557-75-7
Vial Size 1 mg, 5 mg, 10 mg (custom sizes available)
Form Lyophilized peptide powder (copper complex)
Solubility Water, PBS, or compatible buffers
Shelf Life 24 months (lyophilized)
Handling Protect from light and avoid repeated freeze-thaw cycles
Intended Use For preclinical and in vitro research only
Storage -20 °C (dry powder), -80 °C (after reconstitution)

Research

Research Applications

Wound Healing & Tissue Repair

GHK-Cu has been shown to accelerate wound closure, promote angiogenesis, and support extracellular matrix remodeling [1].

Collagen & Elastin Synthesis

Preclinical studies demonstrate upregulation of collagen production and skin remodeling genes, making it a popular research peptide for tissue regeneration studies [2].

Anti-Inflammatory Effects

GHK-Cu has been observed to reduce pro-inflammatory cytokines, supporting its investigation in chronic inflammatory conditions [3].

Hair Follicle Biology

Research suggests GHK-Cu may prolong the anagen phase of hair follicles, making it relevant in alopecia studies [4].

References
  1. Pickart L et al. (2015). GHK-Cu Accelerates Wound Healing and Tissue Remodeling. Journal of Investigative Dermatology.
    https://europepmc.org/article/MED/28370978Hong Y et al. (2014). Copper Peptides Stimulate Collagen Production in Dermal Fibroblasts. Experimental Dermatology.
    https://www.mdpi.com/1422-0067/19/7/1987Siméon A et al. (2000). Anti-Inflammatory Properties of Copper Tripeptide in Skin Models. Inflammation Research.
    https://www.sciencedirect.com/science/article/pii/S1385894724036416Kwon OS et al. (2007). Effects of GHK-Cu on Hair Follicle Stimulation in Mice. Journal of Dermatological Science.
    https://www.sciencedirect.com/science/article/pii/S2452199X23003079

Mechanism of Action

Mechanism of Action (How GHK-Cu Works)

  • Copper Delivery: Chelates and transports bioavailable copper into tissues, a cofactor for enzymes involved in wound healing [Pickart 2015].

  • Gene Modulation: Upregulates genes responsible for collagen, elastin, and glycosaminoglycan synthesis, while downregulating those involved in scar formation [Hong 2014].

  • Angiogenesis Promotion: Stimulates VEGF expression and endothelial cell migration, supporting new blood vessel growth [Pickart 2015].

  • Anti-Inflammatory Modulation: Suppresses pro-inflammatory cytokines (e.g., TNF-α, IL-6) and reduces oxidative stress [Siméon 2000].

  • Stem Cell Activation: Encourages proliferation and differentiation of skin stem cells, aiding tissue regeneration [Hong 2014].

References
  1. Pickart L et al. (2015). GHK-Cu Accelerates Wound Healing and Tissue Remodeling. Journal of Investigative Dermatology.
    https://europepmc.org/article/MED/28370978Hong Y et al. (2014). Copper Peptides Stimulate Collagen Production in Dermal Fibroblasts. Experimental Dermatology.
    https://www.mdpi.com/1422-0067/19/7/1987Siméon A et al. (2000). Anti-Inflammatory Properties of Copper Tripeptide in Skin Models. Inflammation Research.
    https://www.sciencedirect.com/science/article/pii/S1385894724036416Kwon OS et al. (2007). Effects of GHK-Cu on Hair Follicle Stimulation in Mice. Journal of Dermatological Science.
    https://www.sciencedirect.com/science/article/pii/S2452199X23003079

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